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Types of Uveitis

Uveitis is inflammation of the uvea, which is the middle layer of the eye between the retina and the white part of the eye known as the sclera. It is comprised of the iris, the ciliary body, and the choroid. These layers contain many blood vessels — the veins, arteries and capillaries — that carry blood to and from the eye. Because the uvea nourishes many important parts of the eye (such as the retina), inflammation of the uvea can damage your sight.

There are several types of uveitis, defined by the part of the eye where it occurs.

Iritis

Iritis or anterior uveitis affects the front of your eye, between the cornea (the front clear part) and the iris (the colored part) and is the most common type of uveitis.

Intermediate uveitis

Intermediate uveitis refers to inflammation within the middle of the eye, the part filled with the jelly. 

Posterior uveitis

Posterior uveitis refers to inflammation of the retina, the choroid, or the retinal vasculature.

Panuveitis

Panuveitis occurs when all layers of the uvea are inflamed.

50% of the time, uveitis is idiopathic, meaning that an underlying etiology may not be found. A systemic workup is often recommended to rule out other potential causes such as associated autoimmune disease, infection, or even malignancy.

50% of uveitis and scleritis is idiopathic, meaning an underlying cause may not be found.

The other 50% may have an associated condition such as:

  • Ankylosing spondylitis
  • Psoriasis
  • Inflammatory bowel disease (Crohn’s or Ulcerative Colitis)
  • Sarcoidosis 
  • Rheumatoid arthritis
  • Lupus
  • Granulomatous polyangiitis
  • Behcet’s disease
  • Vogt-Koyonagi-Harada disease
  • Shingles (Varicella zoster virus)
  • Herpes simplex virus
  • Syphilis 
  • Tuberculosis
  • Toxoplasmosis 
  • Drug-induced
  • Post-infectious 

Uveitis symptoms may develop suddenly or gradually, in one eye or both, at the same time or within a few weeks. 

There may be redness of the eye, light sensitivity, blurred or decreased vision, new floaters, and/or pain.  Any new symptom should be reported to your ophthalmologist immediately.